Some things do feel worse, yes, but the bladder itself should not have to feel worse before it feels better. If it does, then you should let us know. Examples of things that may feel worse are: cold or flu symptoms, increased vaginal discharge, itching, mild rashes, nausea, headache, cloudy or smelly urination, and fatigue. These symptoms are generally associated with the body going through a cleansing reaction and should pass as improvement in health occurs.