Whem one delves into the dietary past of many of the people sufferring from IC, it is not uncommon to see excessive diet soda drinking or the use of sugar substitutes in coffee, etc... I definitely think this is one more thing that adds fuel to the low level brewing fire that preempts IC. And, after many such things, one day, BOOM, the straw the breaks the camel's back. I think researchers will soon find that there is a direct relationship between this an other toxic chemicals on the bladder tissue.
http://www.naturalnews.com/024316.html