I just got off the phone with my grandmother (step, not blood related) who lives in Guildford, Surrey. She is in her eighties and has suffered with chronic "cystitis" for many, many years. She had a cystoscopy (normal, of course) and continually receives antibiotics (literally for over ten years now). I've told her the basics of Matia's thinking and she seems to understand and definitely thinks it could be IC. She has a history of kidney issues (possibly from birth) and has a tyipcal English diet of lots of tea, crumpets, wine, meats, veggies and sweets.